Boronic acid, B-(5-cyano-2-benzofuranyl)- - Names and Identifiers
Boronic acid, B-(5-cyano-2-benzofuranyl)- - Physico-chemical Properties
Molecular Formula | C9H6BNO3
|
Molar Mass | 186.96 |
Density | 1.40±0.1 g/cm3(Predicted) |
Boling Point | 428.3±48.0 °C(Predicted) |
pKa | 5.67±0.30(Predicted) |
Storage Condition | Inert atmosphere,Store in freezer, under -20°C |
Sensitive | Irritant |
MDL | MFCD18383022 |
Boronic acid, B-(5-cyano-2-benzofuranyl)- - Introduction
(5-Cyanobenzofuran-2-yl)boronic acid((5-Cyanobenzofuran-2-yl)boronic acid) is an organic compound whose chemical formula is C12H8BCNO3. The following is a description of its nature, use, preparation and safety information:
Nature:
(5-Cyanobenzofuran-2-yl)boronic acid is a white solid with low solubility. It is stable at room temperature, but decomposes when heated.
Use:
(5-Cyanobenzofuran-2-yl)boronic acid is a commonly used reagent in organic synthesis, mainly used in coordination chemistry and organic synthesis reactions. It can be used as a boron reagent in organic synthesis for the construction of C- C and C- hetero bonds, for example by Suzuki coupling reactions.
Preparation Method:
(5-Cyanobenzofuran-2-yl) The preparation method of boronic acid can be obtained by reacting benzofuran borate with cyanogen chloride. First, the borate salt of benzofuran undergoes a shrinkage reaction with a sulfinic acid synthesis intermediate to give (5-Cyanobenzofuran-2-yl)boronic acid.
Safety Information:
(5-Cyanobenzofuran-2-yl) The safety data of boronic acid is limited, but under normal circumstances, it is stable at room temperature and not volatile. However, as an organic compound, necessary safety measures should be taken when using it, such as wearing appropriate protective equipment and maintaining good ventilation. Avoid direct contact with skin and eyes, avoid inhaling its dust. If you accidentally touch or take it by mistake, please seek medical advice immediately. When storing, it should be placed in a dry, cool place, and avoid contact with harmful substances such as oxidants.
Last Update:2024-04-10 22:29:15